SUMMARY
Kuzovkova S.D. Histological modifications in human lungs during mycotic invasion with the tuberculosis inflammation. – Manuscript.
Thesis on competition of a scientific degree of the candidate of biological sciences on a speciality 14.03.09 – histology, cytology, embryology. – The A.A. Bogomoletz National medical university, Kiev, 2002.
The thesis is dedicated to definition of histological changes in lung tissues, which were observed during associated micotic lesion and tuberculosis and non-tuberculosis inflammation in human lungs. The presence of every micromicete family is determined to result in certain tissue response, which reflects invasive properties of the fungus. Association of specific tuberculosis with micotic invasion is determined to make a new type of pathology passing which results in decrease the morphologic attributes of specific process activity and in increase of inflammatory changes and necrotic degeneration due to micotic invasion. During non-tuberculosis inflammatory processes micotic lung lesion have its own inflammation attributes, interstitial inflammation development, necrotic tissue degeneration and all bronchi and blood-vessel coat lesion that enhance pathological changes of main disease. Full-grown dark pigmented micromicetes were repeatedly presented during inflammatory processes, which accompanied with necrotic degeneration. Micromicetes, which brought to micotic lung lesion, were not always determined in microbiological studies and in 50.7% cases were determined only by histochemical methods.
Key words: lung tuberculosis, lung mycosis, micromycetes, reaction of tissues.
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